Endocrine Abstracts

Acromegaly is a rare disease with high morbidity and mortality associated with excessive secretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland. In patients with acromegaly, residue may remain after surgical treatment, and disease control is attempted with surgery, medical treatment or radiotherapy for these patients. Pituitary imaging, IGF-1 and GH measurement are used in the follow-ups. Dynamic Contrast Enhancement perfusion MRI provides infor...

Empty sella (ES) is characterized by herniation of the subarachnoid space within the sella, compression and flattening of the pituitary gland. Stretching of the pituitary stalk may also be seen. Empty sella is a frequent finding (5–23%) in autopsy series while it is < 0.01% in persons who undergo medical attention. Meanwhile there is an increase in sellar emptiness with age. Regarding pathophysiology and etiology, it may be primary to the incompetence of the diaphrag...

Background: Paragangliomas (PGLs) and pheochromocytomas (PCCs) arise from chromaffin cells. We evaluated the inflammatory markers. The pan-immune-inflammation value (PIV) has recently been used as a new marker. Therefore, we evaluated the PIV association in patients with PGLs/PCCs.Methods: In the study, the data of 82 patients with PGLs/PCCs who applied between 2005 and 2020 were collected retrospectively from the records. NLR (neutrophil/lymphocyte rati...

Central nervous system involvement is observed in 5-14% of Behçet’s disease and this form is called neurobehçet syndrome (NBS). There are two main forms of CNS involvement in Neurobehçet syndrome, in which parenchymal involvement and vascular involvement are prominent. Cerebral venous thrombosis (CVT), the most prominent form of vascular involvement, has been reported in 8% in Behçet’s disease and in approximately 18% in NBS. Although CVT is the m...

Objective: Data on gender comparisons of diagnosis, management and prognostic factors in Cushing’s disease are very limited, however, there is no such a comparison in ectopic ACTH syndrome (EAS) in the literature. The aim of this study is to compare clinical and hormonal data, neuroendocrine tumor (NET) localization, treatment and survival outcomes in Cushing’s syndrome due to EAS by gender.Material-Methods: Eleven experienced centers from our ...